Microbilogy Lecture Notes (ppt & pdf)

>> Saturday, March 27, 2010

An introduction to the structure of the bacterial cell

Bacterial identification in the diagnostic laboratory versus taxonomy.  
Taxonomic characterization of bacteria. Approaches to rapid diagnosis

Anaerobic and aerobic metabolism. Metabolism of sugars and fatty acids

Structure and synthesis of the cell walls of gram-positive and gram negative bacteria

The mode of action of beta-lactam antibiotics

The mode of action of antibacterial chemotherapeutic agents. Antibiotic susceptibility 
testing. The mechanisms by which bacteria express resistance to antibiotics

The general composition and structure of bacteriophage.
The infectious process and the lytic multiplication cycle.
The lysogenic cycle and its regulation

The mechanisms of gene transfer in bacteria. The nature of transposable
 genetic elements and plasmids. The significance of gene transfer, transposable 
genetic elements and plasmids

The structure and transcription of bacterial genes. The molecular mechanisms 
that bacteria use to regulate gene activity. Inducible and repressible operons. 
The molecular mechanisms involved in catabolite repression and attenuation. 
The ways bacteria regulate enzyme activity

Exotoxins and endotoxins, transmission, adhesion, immunopathology

Enterobacteriaceae, Vibrio, Campylobacter and Helicobacter 

Groups A, B and D  streptococcus, pathogenesis, diagnosis

Streptococcus and pneumonia, Staphylococcus infections, food poisoning, toxic shock

Syphilis, Lyme disease, leptospirosis, gonorrhea, meningitis

Clostridia, gas-gangrene, tetanus, botulism, pseudomonads

Mycobacterial diseases: tuberculois, Legionaires' disease, diphtheria, leprosy

Listeria, Francisella, Brucella, Bacillus and Yersinia Plague, Anthrax, Brucellosis, Listeriosis

Whooping cough, Hib disease

The morphological and physiological characteristics of the mycoplasmas. 
Pathogenesis of mycoplasma infections. Clinical syndromes associated with 
and the epidemiology, diagnosis and treatment of mycoplasma infections

Developmental cycle of chlamydia. Pathogenesis, epidemiology and clinical 
syndromes associated with chlamydia.

Interactions of the Rickettsia, Ehrlichia, Coxiella and Bartonella with the host cell. Pathogenesis, epidemiology and clinical syndromes associated with Rickettsia, Ehrlichia, Coxiella and Bartonella. Methods for treatment, prevention and control of rickettsial diseases.

Credits: University of South Carolina School Of Medicine


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